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81.
Marc Trimborn Rolf-Dieter Wegner Holger Tönnies Nanette Sarioglu Matthias Albig Heidemarie Neitzel 《黑龙江环境通报》2006,26(3):273-276
We describe the first prenatally detected case of a small de novo interstitial duplication of chromosome 16q. This chromosomal aberration is extremely rare. Amniocentesis was indicated by advanced maternal age only. Ultrasound examinations of the foetus showed no abnormalities. Conventional and molecular cytogenetic analyses on cultured amniocytes by comparative genomic hybridisation (CGH) and fluorescence in situ hybridisation (FISH) using partial chromosome paints and a locus-specific YAC clone revealed a de novo direct duplication of the chromosomal region 16q11.2-q13 leading to a partial trisomy 16q (46,XX,dup(16)(q11.2q13)). There are only five postnatal reports of comparable duplications involving this chromosomal region. These patients presented with little or no associated dysmorphic features but with significant neurodevelopmental delay and severe behavioural problems. After genetic counselling, the parents opted for termination of pregnancy. Post-mortem examination showed slight facial dysmorphic signs, minor dysgenesis of the ovaries and an atypical outflow of the arteria thyroidea ima. Copyright © 2006 John Wiley & Sons, Ltd. 相似文献
82.
Henrietta Nittby Bengt Widegren Morten Krogh Gustav Grafström Henrik Berlin Gustav Rehn Jacob L. Eberhardt Lars Malmgren Bertil R. R. Persson Leif G. Salford 《The Environmentalist》2008,28(4):458-465
We have earlier shown that radio frequency electromagnetic fields can cause significant leakage of albumin through the blood–brain
barrier of exposed rats as compared to non-exposed rats, and also significant neuronal damage in rat brains several weeks
after a 2 h exposure to a mobile phone, at 915 MHz with a global system for mobile communications (GSM) frequency modulation,
at whole-body specific absorption rate values (SAR) of 200, 20, 2, and 0.2 mW/kg. We have now studied whether 6 h of exposure
to the radiation from a GSM mobile test phone at 1,800 MHz (at a whole-body SAR-value of 13 mW/kg, corresponding to a brain
SAR-value of 30 mW/kg) has an effect upon the gene expression pattern in rat brain cortex and hippocampus—areas where we have
observed albumin leakage from capillaries into neurons and neuronal damage. Microarray analysis of 31,099 rat genes, including
splicing variants, was performed in cortex and hippocampus of 8 Fischer 344 rats, 4 animals exposed to global system for mobile
communications electromagnetic fields for 6 h in an anechoic chamber, one rat at a time, and 4 controls kept as long in the
same anechoic chamber without exposure, also in this case one rat at a time. Gene ontology analysis (using the gene ontology
categories biological processes, molecular functions, and cell components) of the differentially expressed genes of the exposed
animals versus the control group revealed the following highly significant altered gene categories in both cortex and hippocampus:
extracellular region, signal transducer activity, intrinsic to membrane, and integral to membrane. The fact that most of these
categories are connected with membrane functions may have a relation to our earlier observation of albumin transport through
brain capillaries. 相似文献
83.
Whereas past research has treated co-management of common pool resources as if villagers and project implementing authorities
were the only relevant actors, numerous external factors beyond the control of these two partners create barriers to successful
co-management. This paper draws on discussions with Forest Department officials to examine the influence of these forces on
the outcomes of Joint Forest Management (JFM) in Tamil Nadu, India. An empirical inquiry into the operational aspects of JFM
indicates the important roles of political parties, powerful people, and other state institutions and functionaries as well
as the flow of foreign funding. Further, the strong demand by local people for socio-economic development interventions as
opposed to improvement of degraded forests belittles the role of the Forest Department relative to other departments. Numerous
other conditioning factors and relationships are explored. The authors call for reforms in public governance to allow better
participation of all the actors involved for this participatory management approach to succeed and sustain. 相似文献
84.
85.
Although stewardship has been widely defined and used in environmental management and planning, there is a dearth of studies
that describe how the lay public perceives this concept. A national sample of residents in 14 states who live near DOE nuclear
facilities were interviewed to delineate public understanding and awareness of the stewardship program of the U.S. Department
of Energy (DOE). This study discusses the findings of the survey and discusses how institutional trust influences public participation
and resident’s choices of potential stewards. Almost 40% of the respondents could not define stewardship; those who did, believed
that ‘responsibility,’ ‘management,’ and ‘accountability’ are key elements of stewardship. In addition, about a third of the
respondents identified Federal groups and the DOE as potential stewards.
Readers should send their comments on this paper to: BhaskarNath@aol.com within 3 months of publication of this issue 相似文献
86.
Municipal solid waste (MSW) generation and management in Cuba was studied with a view to integrating composting of the organic fractions of MSW into the system. Composting is already included as part of the environmental strategy of the country as an appropriate waste management solution. However, no programme for area-wide implementation yet exists. The evaluation of studies carried out by some Cuban and international organisations showed that organic matter comprises approximately 60-70% of the MSW, with households being the main source. If all organic waste fractions were considered, the theoretical amount of organic waste produced would be approximately 1 Mio. Mg/a, leading to the production of approximately 0.5 Mio. Mg/a of compost. Composting could, therefore, be a suitable solution for treating the organic waste fractions of the MSW. Composting would best be carried out in decentralised systems, since transportation is a problem in Cuba. Furthermore, low technology and low budget composting options should be considered due to the problematic local economic situation. The location for such decentralised composting units would optimally be located at urban agricultural farms, which can be found all over Cuba. These farms are a unique model for sustainable farming in the world, and have a high demand for organic fertiliser. In this paper, options for the collection and impurity-separation in urban areas are discussed, and a stepwise introduction of source-separation, starting with hotel and restaurant waste, is suggested. For rural areas, the implementation of home composting is recommended. 相似文献
87.
Studies on paleosols under an archaeological landmark of a rare type (a complex of kurgans with “whiskers”) dating from the Early Iron Age (the fourth century AD) have been performed in the steppe zone of the Transural Plateau. The size and shape of third-order soil polygons under stony ridges (“whiskers”) between the kurgans have been described in detail. The results have shown that the paleosol under the kurgans erected at the turn of the Late Sarmatian and Hun times (1600 years ago) is characterized by a higher humus content and deeper location of the carbonate horizon, compared to the recent soil. This indicates that an increase in atmospheric humidity took place in the fourth century AD. 相似文献
88.
Matteo Carpentieri Paolo Giambini Andrea Corti 《Environmental Modeling and Assessment》2008,13(3):415-429
Several wind tunnel experiments of tracer dispersion from reduced-scale landfill models are presented in this paper. Different
experimental set-ups, hot-wire anemometry, particle image velocimetry and tracer concentration measurements were used for
the characterisation of flow and dispersion phenomena nearby the models. The main aim of these experiments is to build an
extensive experimental data set useful for model validation purposes. To demonstrate the potentiality of the experimental
data set, a validation exercise on several mathematical models was performed by means of a statistical technique. The experiments
highlighted an increase in pollutant ground level concentrations immediately downwind from the landfill because of induced
turbulence and mean flow deflection. This phenomenon turns out to be predominant for the dispersion process. Tests with a
different set-up showed an important dependence of the dispersion phenomena from the landfill height and highlighted how complex
orographic conditions downwind of the landfill do not affect significantly the dispersion behaviour. Validation exercises
were useful for model calibration, improving code reliability, as well as evaluating performances. The Van Ulden model proved
to give the most encouraging results. 相似文献
89.
Wastewater treatment works effluent is often considered to be one of the most important point sources of a wide range of anthropogenic contaminants to aquatic systems, however, this paper discusses other potential sources. With the aim of establishing the important sources of UV filters, insect repellent and biocides to the aquatic environment, samples were collected from sites with direct (bathing areas and marinas) and indirect (sites receiving wastewater effluent) human influences. Sunscreens containing UV filters are used in large volumes during the summer months and often applied shortly before a person enters the water for swimming activities. The results presented here demonstrate that washing directly from the skin is an important point source of 4 UV filters to the Oslofjord. The insect repellent, diethyl toluamide, was also measured and it was concluded that washing from the skin was not such an important point source into the fjord. Concentrations of the biocide Irgarol 1051 were also measured and were elevated in the small boat marina and surrounding enclosed area. This work demonstrates that man recreational water-based activities are a diffuse source of some contaminants into coastal and fjord environments and this study provides an initial assessment of the levels being released. 相似文献
90.
Felix Deutsch Jean Vankerkom Liliane Janssen Filip Lefebre Clemens Mensink Frans Fierens Gerwin Dumont Edward Roekens 《Environmental Modeling and Assessment》2008,13(3):431-437
The European Operational Smog (EUROS) integrated air quality modelling system has been extended to model fine particulate
matter (PM). From an extended literature study, the Caltech Atmospheric Chemistry Mechanism and the Model of Aerosol Dynamics,
Reaction, Ionisation and Dissolution were selected and recently coupled to EUROS. Currently, modelling of mass and chemical
composition of aerosols in two size fractions (PM2.5 and PM10–2.5) is possible. The chemical composition is expressed in terms of seven components: ammonium, nitrate, sulphate, elementary
carbon, primary inorganic compounds, primary organic compounds and secondary organic compounds. Calculated PM10 concentrations and chemical composition are presented for two summer months of the year 2003 (1 July to 31 August). 相似文献